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LEAKY GUT
SYNDROME - GUT PERMEABILITY TEST
What is Leaky Gut Syndrome
(LGS):
ü Leaky
Gut Syndrome is a digestive malfunction that occurs in the intestines.
ü The
mucosa (intestinal wall) should
prevent macromolecules (large
undesirable molecules) and undigested food particles from entering the
blood steam and the inside of the body.
ü For
various reasons the integrity of the intestinal wall is compromised and the
Lumina (spaces between the cell wall)
becomes enlarged and results in various substances in the digestive tracts
leaking into the body and blood stream.
ü When
a foreign matter enters the body, be it a food particle, toxin, bacteria,
yeast, parasite, etc, the immune system usually responds to protect the
internal environment causing various symptoms.
ü Intestinal
wall becomes inflamed resulting in numerous digestive and other disorders
ü It
is believed that over time this condition may contribute to a number of
health problems as shown below.
ü Leaky
Gut Syndrome is not usually tested for or diagnosed by you Doctor; despite
the fact significant amount of published research has implicated increased
permeability of the intestinal wall in a large number of illnesses and
allergy.
Definition:
A UK
based Autism charity gives the following definition for leaky gut syndrome
for Allergy Induced Autism (http://www.autismmedical.com/),
it states that Leaky Gut Syndrome is "an increase in permeability of
the intestinal mucosa to luminal macromolecules, antigens and toxins
associated with inflammatory degenerative and/or atrophic mucosal damage".
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Health Problems
associated with LGS
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Accelerated Aging
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Celiac disease
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Endotoxemia
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Malnutrition
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Acne
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Chemotherapy
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Fibromyalgia
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Multiple Chemical Sensitivities
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AIDS
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Chronic Fatigue Syndrome
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Food allergies
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Multiple Sclerosis
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Alcoholism
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Chronic hepatitis
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Food
Intolerance
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Pancreatic dysfunction
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Ankylosing Spondylitis
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Colon cancer
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Giardia
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Psoriasis
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Arthritis
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Crohn's disease
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Hives
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Schizophrenia
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Asthma
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Cystic Fibrosis
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Inflammatory bowel disease
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Ulcerative Colitis
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Autism
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Dermatitis
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Irritable Bowel Syndrome
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Candidiasis
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Eczema
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Liver dysfunction
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About
the test:
ü The gut permeability test is very straight
forward to carry out.
ü The test directly measures the ability of two
non-metabolised sugar molecules, lactulose and mannitol, to permeate the
intestinal mucosa (wall).
ü Lactulose is only slightly absorbed by a healthy
intestinal wall, however if the gut's immune system or barrier integrity is
compromised more will be absorbed through the gut wall.
ü Lactulose thus serves as a marker of mucosal
integrity.
ü Mannitol is easily absorbed therefore serving as
a marker of transcellular uptake.
ü To perform the test a drink of pre-measured
amount of lactulose and mannitol is consumed.
ü The degree of permeability is reflected in the
level of the two sugars recovered in a urine sample collected over the next
6 hours.
ü Full details are supplied with the test.
ü A similar method using PEG400 IS NO LONGER
AVAILABLE
Enquiry: 0800 043 1701
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